Article abstract: Heart-Artery disease are major cause of deaths in industrialized and high-stress countries. Coronary artery atherosclerosis to be the most common cause of morbidity and mortality. Stent invention for CAD treatment was very effective that easily Percutaneous coronary interventions (PCI), including percutaneous transluminal coronary artery angioplasty (PTCA) and coronary artery stenting (CAS).
Coronary stent included metallic scaffold with advance drug therapy. This stents known drug eluting stents (DES). Use of DES remove of limitation of ballon angioplasty but Frist generation of drug eluting stents decrease of in-stent restenosis effectively but delay significantly recovery. In the other hand this stents susceptibility of late thrombosis. This problem led to clear long term clinical complications Therefore, despite obtained improvements, coronary stents still remained no biocompatible with artery.
This review about coronary stent improvement and modification methods that decrease of thrombosis and restenosis. Also the latest progress about coronary implants design that have good biocompatible was offering.