Journal Title: پاییز 91
Article title: Determination of Effectiveness of Antibiotic Prophylaxis for Tension-Free Mesh Hernioplasty

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Article abstract:
Introduction & Objective: The inguinal hernia is a common disorder in general surgery. Various methods have been described in hernia repair. In modern methods, synthetic mesh is used to cover the defect and the most known method is Lichtenstein surgical repair, the present study was done to assess the effectiveness of antibiotic prophylaxis for tension-free mesh hernioplasty. Materials & Methods: In a double blind controlled clinical trial, 200 patients with unilateral inguinal hernia were randomly assigned to either intravenous placebo or antibiotic prophylaxis. A questionnaire containing age, sex, type of anesthesia, duration of surgery and the condition of the wound was filled up for each patient in the study. Data in questionnaire and forms were analyzed with SPSS software version 17 and descriptive statistics and if needed for the evaluation of significance, statistical T-test and chi- square test and even accurate test of Fisher were used. Results: In present study, the mean age of studied persons was 55.49 years with a standard deviation of 12.14 years (the minimum age of participants was 17 year and the maximum was 87 years). Of these patient's, 184 persons (equal to 92%) were male and others were female. The number of wound infections was 3 (3%) in the antibiotic prophylaxis group and 6 (6%) in the placebo group (P = 0.249). Conclusions: These results showed that the differences between the two groups are not statistically significant. Therefore, the routine use of antibiotic prophylaxis for tension-free mesh hernioplasty, may not be necessary. For a definitive statement, study with a larger sample size would be necessary.
Article KeyWords:
Hernioplasty, Antibiotic, Placebo
Article Authors:

	دکتر امیر درخشان‌فر	First Author
	دکتر حمید رضا خورشیدی	Other Author
	دکتر مژگان ممانی	Other Author
	دکتر امین نیایش	Other Author
	دکتر محمد فلاح	Other Author