Journal Title: پاييز 86 Article title: Comparison of Efficacy of Local Piroxicam and Diclofenac in Benign Mastalgia
Article PDF File: Page From: 32 To: 37
Article abstract: Introduction & Objective: Breast pain is a common disorder affecting up to 70% of women during their life. Although most of these women can be managed by reassurance alone, a significant number still require medical treatment.
Topical Non - Steroidal Anti Inflammatory Drugs (NSAIDs) are established as having a palliative effect on mastalgia.
Materials & Methods: A clinical trial study of Piroxicam gel versus Diclofenac gel was carried out, over a period of one year. Fifty female patients attending the outpaint department with severe breast pain were given one of the two agents alternatively, after selection.
Results: The results show that out of 25 patients treated with diclofenac gel, 60% had a clinically significant response after two months of treatment, compared with, 92% with Pyroxicam gel. Only one patient (4%) had side effect with Diclofenac gel.
Conclusions: Piroxicam gel application is more effective, safe and acceptable treatment compared with disolfenac gel for sever cyclic mastalgia.
