Journal Title: بهار 86
Article title: Effect of Antibiotic Prophylaxis in Preventing Wound Infection in Elective Clean Surgical Procedures

Article PDF File:
Page From: 109 To: 114      
Article abstract:
Introduction & Objective: Post operative wound infection is the most common form of infection in surgical patients, containing about 38% of all surgical infections. In the text books surgical wounds are divided into 4 groups: clean, clean- contaminated, contaminated and dirty. Prophylactic antibiotic therapy is recommended only in clean -contaminated operations and is not routine in clean operations except for some special situations. However, prophylactic antibiotic therapy is used for all clean elective operations in Firoozgar hospital that has some disadvantages, including resistant strains of bacteria, and financial problems (extra cost) for patients. This study was done to determine whether antibiotic prophylaxis is an effective method in preventing wound infection in these operations or not. Materials & Methods: This interventional study (clinical trial) was done from June 2002 to May 2003 on 121 patients in Firoozager hospital. Patients who were candidate for elective clean surgical procedures divided into two groups, according to randomized numbers. Results: 62 patients (51.2%) received prophylactic antibiotic and 89 patients (48.8%) received no prophylaxis. Wound infection occurred in 13 patients (10.7%), 7 patients (5.78%) in Control group and 6 patients (4.95%) in antibiotic treatment group. There was no statistically significant difference between two groups. (P=0.1). Conclusions: According to results of this study, routine use of antibiotic prophylaxis is not recommended in clean elective operations.
Article KeyWords:
Antibiotic, Prophylaxis, Infection, Clean
Article Authors:

	دكتر رسول عزيزي	First Author	razizimd@Hotmail.com
	دكتر علي جمشيدي	Other Author
	دكتر محمدعلي تقي‌پور	Other Author