Journal Title: بهار 86 Article title: Effects of Amniotic Fluid in Prevention of Abdominal Adhesion after Laparatomy in Rat Models
Article PDF File: Page From: 38 To: 43
Article abstract: Introduction & Objective: Many studies were done and designed to determine the pathophysiology and to find a way to reduce the formation of adhesion bands after laparatomy. The purpose of our study was to determine the effect of aminiotic fluid in prevention of post laparatomy adhesion formation in rat models.
Materials & Methods: Our study was experimental and laboratory. Thirty adult male rat were used in this study, divided in to two equal groups randomly.
We opened the abdominal wall, then 1 * 1 cm peritoneal layer was excised from the left abdominal wall and 10 longitudinal incision of 2 to 3 cm in length were made on the right parietal peritoneum after that we filled the abdomen of the rats of group I (case group) with 5 cc of amniotic fluid and filled the abdominal of the rats group II (control group) with 5 cc normal saline. Second laparatomy carried out 14 day after the first laparatomy and abdominal adhesion were scored in order to Ahmet Canbaz scale and analyzed with Mann – withney test; P< 0.05 was significant.
Results: After analysis we saw a significant difference between two group (P=0.008). The average of adhesion score were 1.13 +1.3 in group I and 2.5 + 1.18 in group II (P<0.05).
Conclusions: Our study showed that Aminiotic fluid is capable to reduce the formation of adhesion bands after laparatomy.
Article KeyWords: Adhesion Band, Amniotic Fluid, Rat
