Journal Title: بهار 86 Article title: The Role of H.Pylori in Chronic Rhino Sinusitis
Article PDF File: Page From: 88 To: 94
Article abstract: Introduction & Objective: Laryngopharyngeal Reflux (LPR) of gastric content, causes a spectrum of disease including Chronic Rhinosinusitis (CRS). Chronic infection due to H. Pylori is one of the suspected pathophysiology of CRS. Accordingly, this study was planned to determine the role of H. Pylori in CRS and LPR.
Materials & Methods: This is a clinical cohort study. In this study a group of 18 patients with CRS is compared with a group of 18 controls with regards to H. Pylori role in CRS and LPR. PCR, a highly sensitive and specific diagnostic test is used to detect H.Pylori.
Results: H. Pylori was positive only in 2 of 18 CRS patients. This number was 6 for control group. Unexpectedly, there was a reverse correlation between H. Pylori and CRS. Besides, there was no significant relation between positive cases of sinus and gastric samples in each group and between two groups.
Conclusions: H. Pylori has no role in CRS and sinus is just a reservoir of H. Pylori without being afflicted.
