Journal Title: بهار 92
Article title: Ductal Carcinoma Insitu Breast: A Review Article

Article PDF File:
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Article abstract:
Breast cancer is one of the principal causes of mortality in women of 35-65 years old. Ductal Carcinoma Insuitu is a colonal prolifration of suspicious malignant cells which accumulate in breast ducts, with no evidece of invasion to epithelial basement membarane in the neighborhood of stromal tissue. In this review study, we used clinical trials, case- control and open access studies with sufficient validity. Key words like: DCIS, HER-2 new, Tamoxifen, sentinel Lymph node biopsy, for searching in reliable sites (eg: ISI, puBMED, EMBASE) is used. The most important predicting factor for DCIS bahaviour are grade, size and tumor margin. About 50% of tumor cells Presents neuroendocrine marks like: chromogranin A, synaptophysin, CD56, somatostatin. MRI is a very helpful method for DCIS diagnosis. Breast conservative surgery followed by sonography or Mamography is a confident method for patients with DCIS without considering the histological type.
Article KeyWords:
Ductal Carcinoma in Situ, Wide Local Excision, Tamoxifen
Article Authors:

	دکتر مریم حاجی‌لو	First Author
	دکتر حمید رضا علیزاده اطاقور	Other Author	drhralizade@yahoo.com
	دکتر سیدعباس میرمالک	Other Author
	فرزانه یوسفی	Other Author
	سمانه خضرائی	Other Author
	نگار طاهری	Other Author
	محبوبه جعفری	Other Author