The Role of H.Pylori in Chronic Rhino Sinusitis

Naeimi, M.; Seyedi, M.; Ghazvini, K.; Bagheri, M; Afzalaghaee, M.

The Role of H.Pylori in Chronic Rhino Sinusitis

Document Type : Original Article

Authors

M. Naeimi ¹

M. Seyedi ²

K. Ghazvini ³

M Bagheri ⁴

M. Afzalaghaee ⁵

¹ Associate Professor of ENT Surgery, Mashhad University of Medical Sciences and Health Services, Gaem Hospital, Mashhad, Iran

² Specialist of ENT Surgery, Mashhad University of Medical Sciences and Health Services, Gaem Hospital, Mashhad, Iran

³ Assistant Professor of ENT Surgery, Mashhad University of Medical Sciences and Health Services, Gaem Hospital, Mashhad, Iran

⁴ Laboratory Specialist, Mashhad University of Medical Sciences and Health Services, Gaem Hospital, Mashhad, Iran

⁵ Epidemiologist, Mashhad University of Medical Sciences and Health Services, Gaem Hospital, Mashhad, Iran

Abstract

ease including Chronic Rhinosinusitis (CRS). Chronic infection due to H. Pylori is one of the suspected
pathophysiology of CRS. Accordingly, this study was planned to determine the role of H. Pylori in CRS and
LPR.
Materials & Methods: This is a clinical cohort study. In this study a group of 18 patients with CRS is
compared with a group of 18 controls with regards to H. Pylori role in CRS and LPR. PCR, a highly sensitive
and specific diagnostic test is used to detect H.Pylori.
Results: H. Pylori was positive only in 2 of 18 CRS patients. This number was 6 for control group. Unexpectedly,
there was a reverse correlation between H. Pylori and CRS. Besides, there was no significant relation between positive
cases of sinus and gastric samples in each group and between two groups.
Conclusions: H. Pylori has no role in CRS and sinus is just a reservoir of H. Pylori without being
afflicted.

Keywords

H. Pylori

Chronic Rhinosinusitis

Gastro Esophageal Reflux

Laryngopharyngeal Reflux