Introduction & Objective: Significant postoperative pain, defecation problems and relatively long recovery period encouraged researchers to find a safe substitute for conventional Milligan - Morgan hemorrhoidectomy. This study shows the results of our experience with stapled hemorrhoidopexy as one of these methods Material & Methods: From 1999 to 2005, 47 patients (31 male and 16 female) with an average age of 53 years underwent stapled hemorrhoidopexy in Arad General Hospital. All of these patients were prospectively evaluated for 6 months after surgery. The degree of hemorrhoids were grade 2 in 23.4%, grade 3 in 63.9%, grade 4 in 10.6% and one case of rectal prolapse. Results: The average length of operation was 38 min (30-60 min). Mean hospital stay was 1.3 days (1- 3 days). There was no intraoperative complication. The number of 4 cases (8.5%) was complicated: One case with rectal bleeding readmitted 48 hours after surgery. There was no pathologic finding in rectoscopy; after receiving 2 packed cell unit the patient was discharged. In 2 cases of reprolapse, one case was treated by sclerosing injection and the other by local resection of hemorrhoidal pile; and finally, one case with postoperative urinary retention and cystitis had history of urinary problems before the surgery. Neither functional nor incontinency to gas and liquids was presented with a mean follow up of 30 months. Overall of 85.1% (40 cases) of patients were fully satisfied. Conclusions: In spite of severe pain and discomfort and often a prolonged recovery period after conventional operation, stapled hemorrhoidopexy is an effective and safe alternative means of treating prolapsing hemorrhoid. Besides of decreased or eliminated postoperative pain, perioperative and late complications rate were also totally acceptable.