Introduction & Objective: The patency rates of a radial artery graft for CABG approximate 80% at 7 years, although significantly higher patency rates have been reported. Placement of the radial artery graft onto a left-sided target vessel with a high-grade proximal stenosis and good runoff may result in higher patency rates. We evaluated radial artery as a suitable conduit for CABG and measured its early and mid-term results in our 5 years experience. Materials & Methods: From August 1999 to June 2006 radial artery graft was used for CABG in 308 patients. We never dilate radial artery with intraluminal injection. Early and mid term complications and clinical outcomes were evaluated in these patients with a mean follow up of 21±6.2 months. Allen test was performed before operation in all patients. Results: The number of 308 patients (240 male and 68 female) undergoing CABG had one (286) or two (22) distal anastomosis from radial graft conduit in addition to other conduits, patients’ mean age was 55±4.8 years (26-78). The number of 96% of the operations were elective and 4% were urgent. An average of 3.5 grafts per patient was performed. In 18% of the patients, total arterial conduit was used. The operative morbidity was re-operation for bleeding in 2.3%; post-operative-MI in 3.2%; paresthesis in the hand in 10%; stitch abscess in the hand in 3.5%. Mean x-time was 46±9 minutes and the mean CPB time was 85±11 minutes. Hospital mortality was in 0.6%( in 2 patients), in one case directly due to complication of harvesting of radial artery. During the follow up, all the patients are alive, free from cardiac events and have good function classes. Conclusions: Early and mid term results of CABG with radial artery conduit is excellent, and we recommend angiographic studies to establish the true long-term patency of radial artery.