Professor of General Surgery and Gastrointestinal, Liver Disease Research Center, Iran University of Medical Sciences and Health Services, Tehran, Iran
Abstract
In this article after a short review about colorectal carcinoma, recent advances in surgical as well as radiation, adjuvant and neo-adjuvant treatments has been discussed. The preparative and generative causes of primary cells of colorectal cancer is relatively known, but little is known about what initiates the process. We discuss about all recent techniques of total mesorectomy or mesocolectomy, and we also discuss about those patients which have been affected by metastatic lesions and their treatment. There is also discussion about the significance and extent of safe margin in the surgery, the number of resected lymphatic glands (even lymphatic glands smaller than one centimeter), the collaboration of pathologist with the surgeon, the determination of the extent of the disease advancement, and the use of lymphatic map for maximizing the number of resected glands.
