Introduction & Objective: Reductive mammoplasty is one of the most common operations in plastic surgery and inferior pedicle is one of most common techniques. Bottoming out is considered as a long term sequel. Introduced solutions have had satisfactory results. This study wants to present Plication fixation (Pf) as a new technique for minimizing bottoming out. Materials & Methods: 66 patients who were candidates for inferior pedicle reduction mammoplasty were categorized randomly into simple reduction mammoplasty (as inferior pedicle) and inferior pedicle reduction mammoplasty with plication fixation, and underwent appropriate operation. Parameters like operation time, reduced tissue weight, nipple sense, and frequency of bottoming out, were recorded and analyzed. Results: In group 2 (Pf) pedicle lengths was 10±2.2 cm. Asymmetry reduced from 5 to1. Seruma was seen in a patient. In the first group bottoming out was significantly more than in the second group (Pf). Conclusions: Pedicle has vital role in inferior pedicle reduction mammoplasty as far as blood supply and sensibility is concerned. One of its potential complications is bottoming out, as Plication fixation can reduce it significantly. So it seems that placation fixation with little complications, can lead to more long term results in inferior pedicle reduction mammoplasty.