Association between HbA1C Level and Lower Extremity Amputation in Patients with Diabetic Foot

Mozaffar, M.; Mahrami, T; Mosavizadeh, SM

Association between HbA1C Level and Lower Extremity Amputation in Patients with Diabetic Foot

Document Type : Original Article

Authors

M. Mozaffar ¹

T Mahrami ²

SM Mosavizadeh ³

¹ Associate Professor of General Surgery, Shahid Beheshti University of Medical Sciences and Health Services, Shohadaye Tajrish Hospital, Tehran, Iran

² General Surgeon, Shahid Beheshti University of Medical Sciences, Tajrish Martyrs Hospital

³ Assistant Professor, Department of General Surgery, Shahid Beheshti University of Medical Sciences, Shohadaye Tajrish Hospital

Abstract

Introduction & Objective: The lower limb amputations are common musculoskeletal complications of diabetes mellitus and determination of the contributing factors is important for preventive programs. Materials & Methods: In this observational descriptive-comparative cross-sectional study, 100 consecutive patients with diabetic foot attending to Shohada-e-Tajrish Hospital in 2014 and 2015 were enrolled and the association between HbA1C level and lower extremity amputation in them was determined. Results: The results in this study demonstrated that mean hemoglobin A1C levels were 8.5 ± 1.3 and 7.9 ± 1.1 g/dl in those with and without amputation, respectively showing statistically significant difference (P = 0.016). The hemoglobin A1C level was not related to location of limb amputation (P > 0.05). Conclusions: Totally, it may be concluded that there is significant association between HbA1C level and lower extremity amputation in patients with diabetic foot.

Keywords

HbA1C

Lower Extremity Amputation

Diabetic Foot

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