Investigation of Relationship between Gender, Age and Living Place with Outbreak of Acute and Chronic Cholecystetomy and Gall Bladder Carcinoma in Amiralmomenin Hospital of Zabol in 1394

Document Type : Original Article

Authors

1 Assistant Professor of Thoracic Surgery, Zabol University of Medical Sciences and Health Services, Amir-al-Momenin Hospital, Zabol, Iran

2 Medical student, Student Research Committee, Zabol University of Medical Sciences

Abstract
Introduction & Objective: Cholecystitis is one the most common disease in gastrointestinal tract which can be presented as acute or chronic cholecystitis. Several environmental, pathological and physiological factors cause this disease .On the other hand gall bladder carcinoma 2-4 percent of gastrointestinal tract malignancies included, that prevalence in 1 to 2 percent of patients who have cholecystectomy. The outbreak and epidemiologic features of chilecystitis has changed clue to revolutionized style of living. The purpose of this study was to investigation of prevalence of acute, chronic of this disease and gall bladder carcinoma and relation with envirement and physiological parameter patient who have cholecystitis. Materials & Methods: The patient who operated of cholecystectomy in 1394 in Amiralmomenin Hospital of Zabol with diagnosis of cholecystectomy were selected and assessed. The patient were divided into acute, chronic and gallbladder carcinoma groups based on their surgical and pathological finding and patient information records. The data analyzed by using SPSS. Results: 271 patients in the study were evaluated 199 (73.4%) patients were women and 72 (26.6%) patients were men and also 131 (48.3%) patients were living in the villages while 140 (51.7%) patient were living in the city. 142 (52.4%) patients were chronic cholecystitis and 129 (47.6%) patients were acute cholecystitis and 8 patients were gall bladder carcinoma. Gallbladder carcinoma was higher in women (60%). The highest incidence of the gall bladder carcinoma were between 40-50 years (24.7%). The Prevalence of cholecystitis were significant relationship with sex and age. Conclusions: According to this study age, sex and living place is effective in present of cholecystitis (acute, chronic, gallbladder carcinoma).This could be related to hormonal differences personal activity due to the diversity of urban and rural life. In the most patient of gall bladder carcinoma, carcinoma occurs with manifestation of gall stone. So maybe prophylactic cholecystectomy be useful for chronic gall stone.

Keywords


1. Huffman JL, Schenker S. Acute acalculous cholecystitis: a review. Clinical Gastroenterology and Hepatology. 2010; 8(1): 15-22.
2. Vogt DP. Gallbladder disease: an update on diagnosis and treatment. Cleveland Clinic journal of medicine. 2002; 69(12): 977-84.
3. Brunicardi F, Andersen D, Billiar T, Dunn D, Hunter J, Pollock RE. Schwartz's principles of surgery: McGraw-Hill Professional; 2004.
4. Gutkin E, Hussain SA, Kim SH. The Successful Treatment of Chronic Cholecystitis with SpyGlass Cholangioscopy-Assisted Gallbladder Drainage and Irrigation through Self-Expandable Metal Stents. Gut and liver. 2012; 6(1): 136.
5. Jonnalagadda S. Endoscopic therapy of acute cholecystitis. Techniques in gastrointestinal Endoscopy. 2009; 11(1): 13-8.
6. Borzellino G, Sauerland S, Minicozzi AM, Verlato G, Di Pietrantonj C, De Manzoni G, et al. Laparoscopic cholecystectomy for severe acute cholecystitis. A meta-analysis of results. Surgical endoscopy. 2008; 22(1): 8-15.
7. Bergman S, Sourial N, Vedel I, Hanna WC, Fraser SA, Newman D, et al. Gallstone disease in the elderly: are older patients managed differently? Surgical endoscopy. 2011; 25(1): 55-61.
8. Shenghong Z. Thirty cases of chronic cholecystitis treated by acupuncture and oral adiministration of da chai hu tang. Journal of Traditional Chinese Medicine. 2008; 28(3): 173-4.
9. Mulholland M, Lillemoe K, Doherty G, Maier R, Simeone D. Upchurch GR Greenfields Surgery: Scientific Principles & Practice. Michigan: Lippincott Williams; 2010.
10.    Hashemi F, Alamdar S. Correlation between Helicobacter Pylori and Chronic Cholecystitis in Gallbladder Specimens. Razi Journal of Medical Sciences. 2003; 9(31): 623-7.
11.       Gharaibeh KI, Ammari F, Al-Heiss H, Al-Jaberi TM, Qasaimeh GR, Bani-Hani K, et al. Laparoscopic cholecystectomy for gallstones: a comparison of outcome between acute and chronic cholecystitis. Annals of Saudi medicine. 2001; 21(5/6): 312-6.
12.       Hussain MI, Khan A-FA. Outcome of laparoscopic cholecystectomy in acute and chronic cholecystitis. Saudi medical journal. 2006; 27(5): 657-60.
13.       Derakhshanfar A, Niayesh A, GHASEMI FM, HOMAEI J. Assessment of the frequency of complications due to laparoscopic cholecystectomy at Hamedan hospitals (1997-2005). 2008.
14.       Agah S, Fereshtehnejad S, Neshat R. Assessment of the Prevalence of Gallstone in Ultrasonography of Gallbladder and Biliary Duct among Hospitalized Patients in. Razi Journal of Medical Sciences. 2008; 14(57): 7-13.
15.       Schirmer B, Hallowell P. Maingot's abdominal operations. 2013.
16.       Heaton K, Braddon F, Mountford R, Hughes A, Emmett P. Symptomatic and silent gall stones in the community. Gut. 1991; 32(3): 316-20.
17.       Piehler J, Crichlow RW. Primary carcinoma of the gallbladder. Surgery, gynecology & obstetrics. 1978; 147(6): 929-42.
18.       Paraskevopoulos JA, Dennison A, Ross B, Johnson AG. Primary carcinoma of the gallbladder: a 10-year experience. Annals of the Royal College of Surgeons of England. 1992; 74(3): 222.
19.       Voyles CR, Smadja C, Shands WC, Blumgart LH. Carcinoma in choledochal cysts: age-related incidence. Archives of Surgery. 1983; 118(8): 986-8.
20.       Zou S, Zhang L. Relative risk factors analysis of 3,922 cases of gallbladder cancer. Zhonghua wai ke za zhi [Chinese journal of surgery]. 2000; 38(11): 805-8.
21.       Habib FA, Kolachalam RB, Khilnani R, Preventza O, Mittal VK. Role of laparoscopic cholecystectomy in the management of gangrenous cholecystitis. The American journal of surgery. 2001; 181(1): 71-5.
22.       Vitetta L, Sali A, Little P, Mrazek L. Gallstones and gall bladder carcinoma. Australian and New Zealand journal of surgery. 2000; 70(9): 667-73.
23.       Dorostan N, Paziar F, Mirrokni M. Evaluation of Relationship between Complications of Cholecystitis and Gender based on Findings during Laparoscopic Cholecystectomy in Educational Hospitals of Ahvaz. Scientific Medical Journal/Majalleh Elmi Peseshki Daneshgahe Elome Pezeshki Ahwaz. 2011.
24.       Lee H, Han HS, Min S, Lee JH. Sex-based analysis of the outcome of laparoscopic cholecystectomy for acute cholecystitis. British journal of surgery. 2005; 92(4): 463-6.
25.       Rodríguez-Sanjuán JC, Arruabarrena A, Sánchez-Moreno L, González-Sánchez F, Herrera LA, Gómez-Fleitas M. Acute cholecystitis in high surgical risk patients: percutaneous cholecystostomy or emergency cholecystectomy? The American Journal of Surgery. 2012; 204(1): 54-9.
26.       Wudel LJ, Wright JK, Debelak JP, Allos TM, Shyr Y, Chapman WC. Prevention of gallstone formation in morbidly obese patients undergoing rapid weight loss: results of a randomized controlled pilot study. Journal of Surgical Research. 2002; 102(1): 50-6.
27.       Gürleyik G, Gürleyik E, Öztürk A, Ünalmiser S. Gallbladder carcinoma associated with gallstones. Acta Chirurgica Belgica. 2002; 102(3): 203-6.