Rectal Adenocarcinoma Misdiagnosed with Infectious Diarrhea in an 8 Year Old Girl

Document Type : Case Report

Authors

1 Assistant Professor, Department of Pediatric Surgery, Tehran University of Medical Sciences, Children's Medical Center Hospital

2 Assistant Professor, Department of Pathology, Tehran University of Medical Sciences, Children's Medical Center Hospital

3 Pediatric gastroenterologist, Zanjan University of Medical Sciences

4 Assistant Professor of Pediatric Diseases, Tehran University of Medical Sciences

5 Pediatric Surgeon, Tehran University of Medical Sciences, Children’s Medical Center, Tehran, Iran

Abstract
We present an 8-year-old girl presented with rectorrhagia that started since 3 months and misdiagnosed with infectious diarrhea. A few months later, colonoscopy revealed a non-pedunculated polyp and was resected. After the colonoscopy the patient had presentations of peritonitis and rectal perforation was noted in laparotomy. The result of rectal biopsy was adenocarcinoma. Surgery consultant decided to perform a low anterior resection of rectum, ileostomy and the treatment continued with chemotherapy. After 19 month’s follow-ups the patient was alright without any clinical, radiological or laboratory signs or symptoms of tumoral recurrence. As the manifestations of rectal adenocarcinoma are not specific, the clinicians should consider it in the differential diagnosis of gastrointestinal problems.

Keywords


1. R Woods, JO Larkin, C Muldoon, MJ Kennedy, B Mehigan, P McCormick. Metastatic Paediatric Colorectal Carcinoma. Irish medical journal. 2012, 105 (3): 88-9.
2. Pandey A, Gangopadhyay AN, Sharma SP, Kumar V, Gupta DK, Gopal SC, Singh RB. Pediatric carcinoma of rectum – Varanasi experience. Indian Journal of Cancer | July-September 2008 | Volume 45 | Issue 3.
3. King-Jun Koh, Lung-Huang Lin, Shih-Hung Huang, and Jia-Uei Wong. Care-Pediatric Colon Adenocarcinoma. Medicine Volume 94, Number 6, February 2015.
4. Seung Yeon Noh, Seung Young Oh, Soo-Hong Kim, Hyun-Young Kim, Sung-Eun Jung, Kwi-Won Park. Fifteen-year-old colon cancer patient with a 10-year history of ulcerative colitis. World J Gastroenterol 2013 April 21; 19(15): 2437-2440.
5. Raul S. Gonzalez, Sarah C. Shulman, Howard M. Katzenstein, Charlotte K. Steelman, Mark L. Wulkan, Carlos R. Abramowsky, Cynthia Cohen, Gigi K. Davis, and Bahig M. Shehata (2012) Colorectal Adenocarcinoma: A Pediatric Case Review with a Focus on Mismatch Repair Gene Mutations and
E-Cadherin Expression. Pediatric and Developmental Pathology: May/June 2012, Vol. 15, No. 3, pp.
192-198.
6. Warren Hyer, Pediatric Polyposis Syndromes. In: Robert Wyllie, Jeffrey S. Hyams, Marsha Kay, et al, editors. Pediatric Gastrointestinal and Liver Disease, 5th Edition. United States of America: 2016 by Elsevier, Inc: p. 496-507.
7. ZEV H. Davidovics, Neoplasms of the Gastrointestinal Tract. In: Robert Wyllie, Jeffrey S. Hyams, Marsha Kay, et al, editors. Pediatric Gastrointestinal and Liver Disease, 5th Edition. United States of America: 2016 by Elsevier, Inc.: p. 576-578.