strointestinal tract. Numerous studies have shown an association between gallstone disease and lipid
disorders. The aim of this study was to evaluate the serum levels of lipids before and after laparoscopic
cholecystectomy.
Materials & Methods: This cross-sectional study was performed on 88 patients with gallstones
referred to the affiliated hospitals of Babol University of Medical Sciences who underwent laparoscopic
cholecystectomy. Serum levels of triglycerides, cholesterol, high-density lipoprotein and low-density
lipoprotein were measured before surgery and three months after surgery. Data were analyzed by SPSS
software version 16 by T-Test and chi-square tests.
Results: Among 88 patients, 10 cases (11.3%) were men and 78 cases (88.7%) were women. The
mean age of patients was 38/45±13.5. The mean amount of HDL before 5.57+41.61 mg/dl and after
surgery was 5.24+42.74 mg/dl, the mean amount of LDL before and after surgery was 27.3+11.07 mg/dl,
23.7+108.3 mg/dl, the mean amount of serum cholesterol before surgery was 25.8+177.1, after surgery was
20.8+180 mg/dl and the mean amount of serum trigliserid before and after surgery was 31.4+119.1 mg/dl,
46.5+145 mg/dl. Only the serum trigliserid level increased after surgery significantly (P<0.001)
respectively.
Conclusions: This study showed that serum triglyceride levels were significantly increased. Other
parameters were not significantly different.