Background and Objective: Abdominoplasty is a cosmetic surgery that aims to improve the appearance of the abdomen by removing excess skin and fat and tightening the underlying muscles. Evidence has shown that it has effects on physiological functions, especially respiratory function parameters and intra-airway pressure. This study aimed to investigate the effect of abdominoplasty on respiratory function parameters, including forced vital capacity (FVC), forced expiratory volume in one second (FEV1), residual volume (RV), and changes in intra-ductal airway pressure. Materials & Methods: This cross-sectional study was conducted on 36 adult patients who underwent abdominoplasty surgery. Pulmonary function and airway pressure were measured by spirometry before and one week after surgery. The degree of plication was also calculated by measuring abdominal circumference before and after surgery. For statistical analysis and the relationship between respiratory parameters, SPSS version 24 software and paired t-tests and Pearson correlation coefficient were used. Results: In this study, 36 patients with a mean age of 47.7±8.9 years and a plication rate of 0.8±0.06 were enrolled. FVC and FEV1 decreased significantly after surgery. However, one week after surgery, there was a significant increase in residual capacity, potentially indicating a compensatory response (P = 0.009). There was no significant difference in airway pressure before and after surgery, suggesting that abdominoplasty may not directly affect airway compression. A positive and significant correlation was observed between the plication rate and FEV1 and FVC after surgery. In addition, an inverse relationship, although not statistically significant, was observed between plication and residual volume (r = -0.1, P = 0.001). Conclusion: The findings of the present study highlight the temporary reduction in lung capacity after abdominoplasty surgery, along with potential compensatory mechanisms and the role of plication in influencing respiratory function parameters. However, further research with larger sample sizes and longer follow-up periods is necessary to fully understand the impact of abdominoplasty on respiratory function and intra-airway pressure.