Case Report of Breast Cancer Metastasis to Surgical Scar above the Pubis and Literature Review of rare Cases of Breast Cancer Metastasis

Authors

Medical Student, Islamic Azad University, Tehran Medical Branch, Bou Ali Hospital

Abstract
Invasive ductal carcinoma of the breast is one of the most common malignancies in women, with metastasis frequently observed in specific organs such as bones, liver, lungs, and brain. However, metastasis to unusual sites, such as surgical scars, is rare. This article presents a case report of a 55-year-old woman with locally advanced right breast cancer who developed metastasis to an old surgical scar in the pubic area after receiving neoadjuvant chemotherapy and breast-conserving surgery. Several months after treatment, the patient presented to the clinic due to a non-healing wound in the old surgical scar. Histopathological analysis of the scar tissue revealed the presence of metastatic carcinoma of breast origin. Immunohistochemistry confirmed the diagnosis with positive markers GATA3, GCDFP15, CK7, and PAX-8. This report underscores the importance of timely and accurate diagnosis of unusual breast cancer metastases. In this case, local surgical resection combined with radiotherapy was adopted as the therapeutic approach. This study emphasizes the need to consider rare metastatic presentations and conduct thorough examinations of surgical scars in patients with a history of breast cancer. It highlights that even seemingly insignificant lesions may serve as potential metastatic sites.

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