Assistant Professor of General Surgery, Bushehr University of Medical Sciences, Fatemeh Zahra Hospital, Bushehr, Iran
Abstract
Breast cancer is one of the principal causes of mortality in women of 35-65 years old. Ductal Carcinoma Insuitu is a colonal prolifration of suspicious malignant cells which accumulate in breast ducts, with no evidece of invasion to epithelial basement membarane in the neighborhood of stromal tissue. In this review study, we used clinical trials, case- control and open access studies with sufficient validity. Key words like: DCIS, HER-2 new, Tamoxifen, sentinel Lymph node biopsy, for searching in reliable sites (eg: ISI, puBMED, EMBASE) is used. The most important predicting factor for DCIS bahaviour are grade, size and tumor margin. About 50% of tumor cells Presents neuroendocrine marks like: chromogranin A, synaptophysin, CD56, somatostatin. MRI is a very helpful method for DCIS diagnosis. Breast conservative surgery followed by sonography or Mamography is a confident method for patients with DCIS without considering the histological type.
Hajilou M, Alizadeh Otaghvar H, Mirmalek S, Yoosefi F, Khazrayi S, Tahery N, Jafari M. (2013). 'Ductal Carcinoma Insitu Breast: A Review Article', Iranian Journal of Surgery, 21(Spring), pp. 1-16.
CHICAGO
M Hajilou, H Alizadeh Otaghvar, S Mirmalek, F Yoosefi, S Khazrayi, N Tahery and M Jafari, "Ductal Carcinoma Insitu Breast: A Review Article," Iranian Journal of Surgery, 21 Spring (2013): 1-16,
VANCOUVER
Hajilou M, Alizadeh Otaghvar H, Mirmalek S, Yoosefi F, Khazrayi S, Tahery N, Jafari M. Ductal Carcinoma Insitu Breast: A Review Article. Iranian Journal of Surgery. 2013;21(Spring):1-16.
